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Gajewski, Thomas F.

One or more keywords matched the following items that are connected to Gajewski, Thomas F.

Item Type	Name
Concept	Cell Proliferation
Concept	Programmed Cell Death 1 Ligand 2 Protein
Concept	Programmed Cell Death 1 Receptor
Academic Article	B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism.
Academic Article	Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy.
Academic Article	Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells.
Academic Article	Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection.
Academic Article	Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma.
Academic Article	Negative regulation of T-cell function by PD-1.
Academic Article	Peripheral survival of naïve CD8+ T cells.
Academic Article	Homeostatic proliferation of naïve CD8+ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN.
Academic Article	Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.
Academic Article	Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells.
Academic Article	Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer.
Academic Article	Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-?1 phosphorylation.
Academic Article	Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation.
Academic Article	Overcoming immune resistance in the tumor microenvironment by blockade of indoleamine 2,3-dioxygenase and programmed death ligand 1.
Academic Article	PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model.
Academic Article	CD40 ligation reverses T cell tolerance in acute myeloid leukemia.
Academic Article	Therapeutic activity of high-dose intratumoral IFN-ß requires direct effect on the tumor vasculature.
Academic Article	STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article	Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells.
Academic Article	Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Academic Article	MYC - a thorn in the side of cancer immunity.
Academic Article	Molecular Drivers of the Non-T-cell-Inflamed Tumor Microenvironment in Urothelial Bladder Cancer.
Academic Article	NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells.
Academic Article	Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.
Academic Article	Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy.
Academic Article	The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients.
Academic Article	Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.
Academic Article	Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy.
Academic Article	Pseudoprogression manifesting as recurrent ascites with anti-PD-1 immunotherapy in urothelial bladder cancer.
Academic Article	Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response.
Academic Article	Secondary resistance to immunotherapy associated with ß-catenin pathway activation or PTEN loss in metastatic melanoma.
Academic Article	Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-?-signaling mutant cancer cells.
Academic Article	Strategies to overcome resistance to PD-1 inhibitors.
Academic Article	Antibody and T cell responses to COVID-19 vaccination in patients receiving anticancer therapies.
Academic Article	Checkpoint Blockade-Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines.

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Cell proliferation
cell death